Journal article icon

Journal article

Environmental variation alters the fitness effects of rifampicin resistance mutations in Pseudomonas aeruginosa.

Abstract:

The fitness effects of antibiotic resistance mutations in antibiotic-free conditions play a key role in determining the long-term maintenance of resistance. Although resistance is usually associated with a cost, the impact of environmental variation on the cost of resistance is poorly understood. Here we test the impact of heterogeneity in temperature and resource availability on the fitness effects of antibiotic resistance using strains of the pathogenic bacterium Pseudomonas aeruginosa carr...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1111/evo.12880

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
More from this funder
Name:
European Research Council
Grant:
281591
More from this funder
Name:
Royal Society
Funding agency for:
MacLean, C
More from this funder
Name:
Somerville College, Oxford
Funding agency for:
Gifford, D
More from this funder
Name:
Clarendon Fund
Funding agency for:
Gifford, D
More from this funder
Name:
Natural Sciences and Engineering Research Council of Canada
Funding agency for:
Gifford, D
Publisher:
Wiley
Journal:
Evolution; international journal of organic evolution More from this journal
Volume:
70
Issue:
3
Pages:
725–730
Publication date:
2016-03-01
Acceptance date:
2016-02-04
DOI:
EISSN:
1558-5646
ISSN:
0014-3820
Language:
English
Keywords:
Pubs id:
pubs:605982
UUID:
uuid:f6dfb8cc-4e4d-4a99-8ede-9b1dca83be1d
Local pid:
pubs:605982
Source identifiers:
605982
Deposit date:
2016-02-26

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP