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Phenotyping airways disease: an A to E approach.

Abstract:

The airway diseases asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous conditions with overlapping pathophysiological and clinical features. It has previously been proposed that this heterogeneity may be characterized in terms of five relatively independent domains labelled from A to E, namely airway hyperresponsiveness (AHR), bronchitis, cough reflex hypersensitivity, damage to the airways and surrounding lung parenchyma, and extrapulmonary factors. Airway hyperrespons...

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Authors


Wardlaw, AJ More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine
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Journal:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Volume:
42
Issue:
12
Pages:
1664-1683
Publication date:
2012-12-05
DOI:
EISSN:
1365-2222
ISSN:
0954-7894
URN:
uuid:f6d5e490-cf3e-4eb4-8469-72e95318ddf6
Source identifiers:
423836
Local pid:
pubs:423836

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