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Effects of dopamine and domperidone on ventilation during isocapnic hypoxia in humans.

Abstract:

In order to investigate the role of dopamine in the ventilatory response to sustained, isocapnic hypoxia six subjects were studied three times in each of three pharmacological conditions: (1) in the absence of any drug administration, (2) during i.v. infusion of dopamine (3 micrograms.kg-1.min-1), and (3) after pretreatment with domperidone. Otherwise the experimental protocol was identical on each day and consisted of holding the subjects' end-tidal PO2 at 100 Torr for 10 min, then 50 Torr f...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Respiration physiology
Volume:
85
Issue:
3
Pages:
319-328
Publication date:
1991-09-05
DOI:
ISSN:
0034-5687
URN:
uuid:f6d0b313-6d5a-4261-a4d8-17b627bc1a6c
Source identifiers:
113499
Local pid:
pubs:113499

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