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Journal article

Immunology of pre-eclampsia.

Abstract:

Pre-eclampsia develops in stages, only the last being the clinical illness. This is generated by a non-specific, systemic (vascular), inflammatory response, secondary to placental oxidative stress and not by reactivity to fetal alloantigens. However, maternal adaptation to fetal (paternal alloantigens) is crucial in the earlier stages. A pre-conceptual phase involves maternal tolerization to paternal antigens by seminal plasma. After conception, regulatory T cells, interacting with indoleamin...

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Publication status:
Published

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Authors


Redman, CW More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Journal:
American journal of reproductive immunology (New York, N.Y. : 1989)
Volume:
63
Issue:
6
Pages:
534-543
Publication date:
2010-06-05
DOI:
EISSN:
1600-0897
ISSN:
1046-7408
URN:
uuid:f6b1990e-5ef0-42fd-b2ed-b6d9c0ad030e
Source identifiers:
248254
Local pid:
pubs:248254

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