Thesis
Role of histones in DNA double-strand break repair in Dictyostelium
- Abstract:
-
Correct repair of DNA double-strand breaks is crucial for maintenance of genome integrity. Despite data showing the importance of histones variants and histone post-translational modifications in the cellular response to DNA damage, there is still a lack of knowledge concerning the role of histone H3 and its variants as well as histone ADP-ribosylation in such processes. In this work Dictyostelium discoideum was employed as genetically tractable model organism to address the role ...
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Subjects:
- UUID:
-
uuid:f6ae6f6a-9f83-4326-89e3-719ea9c43cc0
- Deposit date:
- 2016-04-11
Terms of use
- Copyright holder:
- Rakhimova, A
- Copyright date:
- 2015
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