Journal article icon

Journal article

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics (The DART-AD Trial)

Abstract:

Background: There have been increasing concerns regarding the safety and efficacy of neuroleptics in people with dementia, but there are very few long-term trials to inform clinical practice. The aim of this study was to determine the impact of long-term treatment with neuroleptic agents upon global cognitive decline and neuropsychiatric symptoms in patients with Alzheimer disease. Methods and findings. Design: randomised, blinded, placebo-controlled parallel two-group treatment discontinuati...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pmed.0050076

Authors


More by this author
Institution:
"King's College London, London, UK"
Department:
Wolfson Centre for Age-Related Diseases
Role:
Author
More by this author
Institution:
"Northgate Hospital, Morpeth, Northumberland, UK"
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
More by this author
Institution:
"Newcastle University, Newcastle upon Tyne, UK"
Department:
Department of Psychiatry
Role:
Author
More by this author
Institution:
"Oxfordshire and Buckinghamshire Mental Health NHS Trust", "University of Oxford"
Department:
Medical Sciences Division - Psychiatry
Role:
Author
More from this funder
Name:
Alzheimer's Research Trust, Cambridge, UK
Funding agency for:
Ballard, C
McShane, R
Jacoby, R
Publisher:
Public Library of Science
Journal:
PLoS Medicine More from this journal
Volume:
5
Issue:
4
Article number:
e76
Publication date:
2008-04-01
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Language:
English
Keywords:
Subjects:
UUID:
uuid:f699950a-83dd-48ff-909d-9ee71ac69010
Local pid:
ora:2506
Deposit date:
2009-01-09

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP