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Journal article

Genomic stability and tumorigenesis.

Abstract:

Cancer research needs to explain the observed incidence of cancer. Many factors determine this process, including: the number of susceptible cells in the tissue of origin; the number of normal cell divisions through which susceptible cells pass in normal development and turnover; the number of cell divisions during tumorigenesis; the selective advantage which tumour cells have acquired; the ease of detection of a cancer; the number of mutations which are required for malignancy; the possible ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Journal:
Seminars in cancer biology
Volume:
15
Issue:
1
Pages:
61-66
Publication date:
2005-02-05
DOI:
EISSN:
1096-3650
ISSN:
1044-579X
URN:
uuid:f692cc56-0a46-44c6-8443-76e56c6e7238
Source identifiers:
72040
Local pid:
pubs:72040

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