Journal article icon

Journal article

A model for chondrogenic condensations in the developing limb: the role of extracellular matrix and cell tractions.

Abstract:

The hyaluronate component of the extracellular matrix is a powerfully hydrophilic polymer, capable of osmotically swelling and deswelling by a volume factor of 5 or more. At the time of cartilage condensation in the limb bud the chondrocytes start to produce hyaluronidase, an enzyme which degrades hyaluronate. The consequent deswelling brings the chondrocytes closer together - close enough for intercellular cell tractions to become effective and intercellular junctions to form. By analysing t...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
Journal:
Journal of embryology and experimental morphology
Volume:
89
Issue:
OCT
Pages:
93-112
Publication date:
1985-10-05
ISSN:
0022-0752
URN:
uuid:f68eb8d4-e61b-4f56-8eb8-58093d45e133
Source identifiers:
22568
Local pid:
pubs:22568

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP