Journal article icon

Journal article

The effect of genome-wide association scan quality control on imputation outcome for common variants.

Abstract:

Imputation is an extremely valuable tool in conducting and synthesising genome-wide association studies (GWASs). Directly typed SNP quality control (QC) is thought to affect imputation quality. It is, therefore, common practise to use quality-controlled (QCed) data as an input for imputing genotypes. This study aims to determine the effect of commonly applied QC steps on imputation outcomes. We performed several iterations of imputing SNPs across chromosome 22 in a dataset consisting of 3177 ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1038/ejhg.2010.242

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Expand authors...
Journal:
Eur J Hum Genet
Volume:
19
Issue:
5
Pages:
610-614
Publication date:
2011-05-05
DOI:
EISSN:
1476-5438
ISSN:
1018-4813
URN:
uuid:f68c5c7b-a211-450f-baa4-39bd14bba603
Source identifiers:
115726
Local pid:
pubs:115726

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP