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Virus genomes reveal factors that spread and sustained the Ebola epidemic

Abstract:

The 2013–2016 epidemic of Ebola virus disease was of unprecedented magnitude, duration and impact. Analysing 1610 Ebola virus genomes, representing over 5% of known cases, we reconstruct the dispersal, proliferation and decline of Ebola virus throughout the region. We test the association of geography, climate and demography with viral movement among administrative regions, inferring a classic ‘gravity’ model, with intense dispersal between larger and closer populations. Despite attenuation o...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/nature22040

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
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Name:
United States Agency for International Development
Grant:
OAA-G-15-00001
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Name:
Fred Hutchinson Cancer Research Center
Grant:
Mahan Post-doctoral fellowship (G.D.
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Name:
National Natural Science Foundation of China
Grant:
1590760
81321063(G.F.G
More from this funder
Name:
Ministry of Science and Technology of China
Grant:
DevelopmentProgram2016YFC1200800 (D.L
KeyResearch
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Name:
National Institute for Health Research
Grant:
HealthProtectionResearchUnitinEmerging
ZoonoticInfections(J.A.H
Publisher:
Springer Nature
Journal:
Nature More from this journal
Volume:
544
Issue:
7650
Pages:
309–315
Publication date:
2017-04-12
Acceptance date:
2017-03-02
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Pubs id:
pubs:683787
UUID:
uuid:f689d2e4-b69b-47bd-b30d-7dbc41e24236
Local pid:
pubs:683787
Source identifiers:
683787
Deposit date:
2017-03-02

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