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Continuum approximations for lattice-free multi-species models of collective cell migration

Abstract:

Cell migration within tissues involves the interaction of many cells from distinct subpopulations. In this work, we present a discrete model of collective cell migration where the motion of individual cells is driven by random forces, short range repulsion forces to mimic crowding, and longer range attraction forces to mimic adhesion. This discrete model can be used to simulate a population of cells that is composed of K ≥ 1 distinct subpopulations. To analyse the discrete model we formulate ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jtbi.2017.04.009

Authors


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Institution:
University of Oxford
Oxford college:
St Hugh's College
Role:
Author
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Name:
Australian Research Council
Grant:
DP170100474
Publisher:
Elsevier
Journal:
Journal of Theoretical Biology More from this journal
Volume:
422
Pages:
1-11
Publication date:
2017-04-08
Acceptance date:
2017-04-07
DOI:
EISSN:
1095-8541
ISSN:
0022-5193
Language:
English
Keywords:
Pubs id:
pubs:689392
UUID:
uuid:f679dd5b-59b9-4c30-bbda-2914943439fc
Local pid:
pubs:689392
Source identifiers:
689392
Deposit date:
2017-04-24

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