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Comparison of hyperpolarized (3)He MRI with Xe-enhanced computed tomography imaging for ventilation mapping of rat lung.

Abstract:

Lung ventilation was mapped in five healthy Brown Norway rats (210-377 g) using both hyperpolarized (3)He MRI and Xe-enhanced computed tomography (Xe-CT) under similar ventilator conditions. Whole-lung measurements of ventilation r obtained with (3)He MRI were not significantly different from those obtained from Xe-CT (p = 0.1875 by Wilcoxon matched pairs test). The ventilation parameter r is defined as the fraction of refreshed gas per unit volume per breath. Regional ventilation was also me...

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Publication status:
Published

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Publisher copy:
10.1002/nbm.1659

Authors


Santyr, GE More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Ouriadov, A More by this author
Drangova, M More by this author
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Journal:
NMR in biomedicine
Volume:
24
Issue:
9
Pages:
1073-1080
Publication date:
2011-11-05
DOI:
EISSN:
1099-1492
ISSN:
0952-3480
URN:
uuid:f65a6f82-60f8-43ea-80a6-82c28e0ba9fe
Source identifiers:
441909
Local pid:
pubs:441909

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