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Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures.

Abstract:

Two monoclonal antibodies, anti-Ti1A and anti-Ti1B, were shown to define the clonally unique surface receptor on CT8III, a human cytolytic T lymphocyte specific for a class I major histocompatibility gene product. In the present report, this surface structure was characterized and related to the 20-kilodalton (kDa) T3 glycoprotein present on all mature human T lymphocytes. The results demonstrated that the anti-clonotypic antibodies react with an epitope on a disulfide-linked heterodimer of 4...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.80.13.4104

Authors


Reinherz, EL More by this author
Fitzgerald, KA More by this author
Hussey, RE More by this author
Hodgdon, JC More by this author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
80
Issue:
13
Pages:
4104-4108
Publication date:
1983-07-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:f6547139-0ec0-4041-9dd7-3566bd74ea75
Source identifiers:
14304
Local pid:
pubs:14304

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