Journal article icon

Journal article

Polymorphisms of transporter sssociated with antigen presentation, tumor necrosis factor-α and interleukin-10 and their implications for protection and susceptibility to severe forms of dengue fever in patients in Sri Lanka.

Abstract:

Context

To date, a clear understanding of dengue disease pathogenesis remains elusive. Some infected individuals display no symptoms while others develop severe life-threatening forms of the disease. It is widely believed that host genetic factors influence dengue severity.

Aims

This study evaluates the relationship between certain polymorphisms and dengue severity in Sri Lankan patients.

Settings and Design

Polymorphism studies are carried out on g...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.4103/0974-777x.170501

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
More from this funder
Name:
Genetech Research Institute
More from this funder
Name:
The Centre for Dengue Research, University of Sri Jayewardenepura
Publisher:
Medknow Publications
Journal:
Journal of Global Infectious Diseases More from this journal
Volume:
7
Issue:
4
Pages:
157-164
Publication date:
2015-11-01
DOI:
EISSN:
0974-8245
ISSN:
0974-777X
Language:
English
Keywords:
Pubs id:
pubs:588679
UUID:
uuid:f65461d5-fc1b-4262-830f-92624f4171fc
Local pid:
pubs:588679
Source identifiers:
588679
Deposit date:
2016-03-30

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP