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Journal article

Haplotypic analysis of the TNF locus by association efficiency and entropy.

Abstract:

BACKGROUND: To understand the causal basis of TNF associations with disease, it is necessary to understand the haplotypic structure of this locus. We genotyped 12 single-nucleotide polymorphisms (SNPs) distributed over 4.3 kilobases in 296 healthy, unrelated Gambian and Malawian adults. We generated 592 high-quality haplotypes by integrating family- and population-based reconstruction methods. RESULTS: We found 32 different haplotypes, of which 13 were shared between the two populations. Bot...

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Publication status:
Published

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Publisher copy:
10.1186/gb-2003-4-4-r24

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Journal:
Genome biology
Volume:
4
Issue:
4
Pages:
R24
Publication date:
2003-01-01
DOI:
EISSN:
1465-6914
ISSN:
1465-6906
URN:
uuid:f64fa917-fd23-4cd5-b387-c990ab52f5c4
Source identifiers:
32351
Local pid:
pubs:32351

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