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How to improve quality of research in intensive care medicine

Abstract:

This paper discusses several approaches to improve quality of research in intensive care medicine. The baseline standard of care is important in randomized controlled trials. If standard of care is low, trialists could consider improving this before starting the trial. Implementation studies and efficacy trials should not be mixed up. Trialists could further try to increase prognostic as well as predictive enrichment, e.g., through biological phenotyping. Robustness of statistical findings ca...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.21037/atm.2018.01.18

Authors


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Role:
Author
ORCID:
0000-0003-2911-4549
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Publisher:
AME Publishing Company Publisher's website
Journal:
Annals of Translational Medicine Journal website
Volume:
6
Issue:
2
Article number:
35
Publication date:
2018-01-22
Acceptance date:
2018-01-08
DOI:
EISSN:
2305-5847
ISSN:
2305-5839
Pmid:
29430452
Source identifiers:
824877
Language:
English
Keywords:
Pubs id:
pubs:824877
UUID:
uuid:f64a4852-aa32-4024-9dae-6ad3546c1ed8
Local pid:
pubs:824877
Deposit date:
2018-11-22

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