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Journal article

The tail of integrin activation.

Abstract:

Integrins are essential adhesion receptors found on the surfaces of all metazoan cells. As regulators of cell migration and extracellular matrix assembly, these membrane-spanning heterodimers are critical for embryonic development, tissue repair and immune responses. Signals transmitted by integrins from outside to inside the cell promote cell survival and proliferation, but integrin affinity for extracellular ligands can also be controlled by intracellular cues. This bidirectional signaling ...

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Publisher copy:
10.1016/j.tibs.2010.11.002
Journal:
Trends in biochemical sciences More from this journal
Volume:
36
Issue:
4
Pages:
191-198
Publication date:
2011-04-01
DOI:
ISSN:
0968-0004
Language:
English
Keywords:
Pubs id:
pubs:246588
UUID:
uuid:f6383bda-f578-47d0-a5d8-7867a383df78
Local pid:
pubs:246588
Source identifiers:
246588
Deposit date:
2012-12-19

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