Methodological problems in the use of indirect comparisons for evaluating healthcare interventions: survey of published systematic reviews.
OBJECTIVE: To investigate basic assumptions and other methodological problems in the application of indirect comparison in systematic reviews of competing healthcare interventions. DESIGN: Survey of published systematic reviews. Inclusion criteria Systematic reviews published between 2000 and 2007 in which an indirect approach had been explicitly used. DATA EXTRACTION: Identified reviews were assessed for comprehensiveness of the literature search, method for indirect comparison, and whether ...Expand abstract
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