- Abstract:
-
1. A dose finding pharmacokinetic study was performed in 20 Karen women in the third trimester of pregnancy receiving antimalarial prophylaxis with mefloquine. Ten received 250 mg mefloquine base weekly and ten received identical tablets of 125 mg base/week. 2. Both dose regimens were well tolerated. Malaria was prevented effectively, there were no serious adverse effects, all pregnancies proceeded normally, and there were no abnormalities in the babies followed up to 2 years. 3. The median t...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1365-2125.1990.tb03746.x
-
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- Journal:
- British journal of clinical pharmacology
- Volume:
- 30
- Issue:
- 1
- Pages:
- 79-85
- Publication date:
- 1990-07-05
- DOI:
- EISSN:
-
1365-2125
- ISSN:
-
0306-5251
- URN:
-
uuid:f6182e4c-63bf-4148-ab3a-cb1d1adb9732
- Source identifiers:
-
12193
- Local pid:
- pubs:12193
- Language:
- English
- Keywords:
- Copyright date:
- 1990
Journal article
Mefloquine antimalarial prophylaxis in pregnancy: dose finding and pharmacokinetic study.
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