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Granulocyte transfusions for preventing infections in people with neutropenia or neutrophil dysfunction

Abstract:

Despite modern antimicrobials and supportive therapy, bacterial and fungal infections are still major complications in people with prolonged disease-related or therapy-related neutropenia. Since the late 1990s there has been increasing demand for donated granulocyte transfusions to treat or prevent severe infections in people who lack their own functional granulocytes. This is an update of a Cochrane review first published in 2009.To determine the effectiveness and safety of prophylactic gran...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/14651858.CD005341.pub3

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Role:
Author


Publisher:
Wiley
Journal:
Cochrane Database of Systematic Reviews More from this journal
Volume:
2015
Issue:
6
Pages:
CD005341
Publication date:
2015-09-29
DOI:
EISSN:
1469-493X
ISSN:
1361-6137


Language:
English
Pubs id:
pubs:343835
UUID:
uuid:f61255f2-2820-41e2-9c6d-dbe08c174a3c
Local pid:
pubs:343835
Source identifiers:
343835
Deposit date:
2016-02-11
ARK identifier:

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