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Journal article

A pericentric inversion of chromosome six in a patient with Peutz-Jeghers' syndrome and the use of FISH to localise the breakpoints on a genetic map.

Abstract:

Karyotypic analysis in a patient with Peutz-Jeghers' syndrome demonstrated a pericentric inversion on chromosome 6. Further investigation was undertaken using fluorescence in situ hybridisation (FISH) with yeast artificial chromosome clones selected to contain genetic markers from chromosome 6, and a probe for the centromeric alphoid repeat array. This analysis located one inversion breakpoint within the alphoid array, in a 1-cM interval between D6S257 and D6S402, and the other in a 4-cM inte...

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Publication status:
Published

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Publisher copy:
10.1007/s004390050173

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Human genetics More from this journal
Volume:
98
Issue:
2
Pages:
125-128
Publication date:
1996-08-01
DOI:
EISSN:
1432-1203
ISSN:
0340-6717
Language:
English
Keywords:
Pubs id:
pubs:45229
UUID:
uuid:f5fbb185-0da4-49bb-a9e8-4abfa9015d6c
Local pid:
pubs:45229
Source identifiers:
45229
Deposit date:
2012-12-19

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