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Journal article

A pericentric inversion of chromosome six in a patient with Peutz-Jeghers' syndrome and the use of FISH to localise the breakpoints on a genetic map.

Abstract:

Karyotypic analysis in a patient with Peutz-Jeghers' syndrome demonstrated a pericentric inversion on chromosome 6. Further investigation was undertaken using fluorescence in situ hybridisation (FISH) with yeast artificial chromosome clones selected to contain genetic markers from chromosome 6, and a probe for the centromeric alphoid repeat array. This analysis located one inversion breakpoint within the alphoid array, in a 1-cM interval between D6S257 and D6S402, and the other in a 4-cM inte...

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Publication status:
Published

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Publisher copy:
10.1007/s004390050173

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
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Journal:
Human genetics
Volume:
98
Issue:
2
Pages:
125-128
Publication date:
1996-08-05
DOI:
EISSN:
1432-1203
ISSN:
0340-6717
URN:
uuid:f5fbb185-0da4-49bb-a9e8-4abfa9015d6c
Source identifiers:
45229
Local pid:
pubs:45229

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