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A new monospecific ovine Fab fragment antivenom for treatment of envenoming by the Sri Lankan Russell's viper (Daboia Russelii Russelii): a preliminary dose-finding and pharmacokinetic study.

Abstract:

Russell's viper is the most important cause of life-threatening snake bite and acute renal failure in Sri Lanka. Only equine polyspecific antivenoms imported from India are available. They have not proved effective clinically or in clearing venom antigenemia and they frequently cause reactions. In an attempt to reduce mortality and morbidity, a new monospecific ovine Fab fragment antivenom (PolongaTab; Therapeutic Antibodies, Inc., London, United Kingdom) was raised against Sri Lankan Russell...

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Publication status:
Published

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Authors


Ariaratnam, CA More by this author
Eddleston, M More by this author
Kuleratne, SA More by this author
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Journal:
The American journal of tropical medicine and hygiene
Volume:
61
Issue:
2
Pages:
259-265
Publication date:
1999-08-05
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:f5e1722c-0872-4534-ab2b-bd2a9533b073
Source identifiers:
60972
Local pid:
pubs:60972

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