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Electroencephalographic response to sodium nitrite may predict delayed cerebral ischemia after severe subarachnoid hemorrhage.

Abstract:

Objective

Aneurysmal subarachnoid haemorrhage (SAH) often leads to death and poor clinical outcome. Injury occurring during the first 72 hours is termed early brain injury (EBI), with disruption of the nitric oxide (NO) pathway playing an important pathophysiological role in its development. Quantitative electroencephalography (qEEG) parameters such as alpha/delta frequency ratio (ADR) are surrogate markers of cerebral ischaemia. This study assessed the qEEG ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1097/CCM.0000000000001950

Authors


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Department:
Oxford, MSD, Clinical Neurosciences
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Department:
Oxford, MSD, Clinical Neurosciences
More by this author
Department:
Oxford, MSD, Clinical Neurosciences
Herigstad, M More by this author
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Funding agency for:
Rowland, MJ
National Institute for Health Research More from this funder
Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Critical Care Medicine Journal website
Volume:
44
Issue:
11
Pages:
e1067–e1073
Publication date:
2016-08-09
Acceptance date:
2016-03-25
DOI:
EISSN:
1530-0293
ISSN:
0090-3493
Pubs id:
pubs:636651
URN:
uri:f5de637a-7b36-464a-8cc4-1b2882037ac8
UUID:
uuid:f5de637a-7b36-464a-8cc4-1b2882037ac8
Local pid:
pubs:636651

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