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Mesenchymal stromal cells; role in tissue repair, drug discovery and immune modulation.

Abstract:

Mesenchymal stromal cells (MSCs) participate in repair of damaged tissues, possess the potential to serve as a useful tool in the drug discovery field and exert immunosuppressive effects as demonstrated by their ability to modulate the immune response. Herein, the roles played by MSC differentiation and/or production of trophic factors involved in tissue repair are discussed. MSCs offer the opportunity to probe targets that conventional or differentiated cell lines do not express; thus provid...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
Publisher:
Bentham Science Publishers B.V.
Journal:
Current drug delivery
Volume:
11
Issue:
5
Pages:
561-571
Publication date:
2014-01-01
DOI:
EISSN:
1875-5704
ISSN:
1567-2018
URN:
uuid:f5d8ea8f-36a0-45af-8248-f678a9ab1a70
Source identifiers:
491060
Local pid:
pubs:491060

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