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The effect of selection on genealogies.

Abstract:

The coalescent process can describe the effects of selection at linked loci only if selection is so strong that genotype frequencies evolve deterministically. Here, we develop methods proposed by Kaplan, Darden, and Hudson to find the effects of weak selection. We show that the overall effect is given by an extension to Price's equation: the change in properties such as moments of coalescence times is equal to the covariance between those properties and the fitness of the sample of genes. The...

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Publication status:
Published

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Publisher copy:
10.1534/genetics.166.2.1115

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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
Role:
Author
Journal:
Genetics
Volume:
166
Issue:
2
Pages:
1115-1131
Publication date:
2004-02-05
DOI:
EISSN:
1943-2631
ISSN:
0016-6731
URN:
uuid:f5d7106b-b3c1-4e45-9bb7-8a08c3315545
Source identifiers:
97458
Local pid:
pubs:97458

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