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Estimating recombination rates from population-genetic data.

Abstract:

Obtaining an accurate measure of how recombination rates vary across the genome has implications for understanding the molecular basis of recombination, its evolutionary significance and the distribution of linkage disequilibrium in natural populations. Although measuring the recombination rate is experimentally challenging, good estimates can be obtained by applying population-genetic methods to DNA sequences taken from natural populations. Statistical methods are now providing insights into...

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Publisher copy:
10.1038/nrg1227

Authors


Stumpf, MP More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics, Clinical Medicine
Journal:
Nature reviews. Genetics
Volume:
4
Issue:
12
Pages:
959-968
Publication date:
2003-12-05
DOI:
EISSN:
1471-0064
ISSN:
1471-0056
URN:
uuid:f5cf9e3b-5e0b-4cd0-89f7-60664fffa5b8
Source identifiers:
97701
Local pid:
pubs:97701

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