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People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population

Abstract:

There is a great deal of interest in a fine-scale population structure in the UK, both as a signature of historical immigration events and because of the effect population structure may have on disease association studies. Although population structure appears to have a minor impact on the current generation of genome-wide association studies, it is likely to have a significant part in the next generation of studies designed to search for rare variants. A powerful way of detecting such struct...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/ejhg.2011.127

Authors


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Institution:
University of Oxford
Department:
Medical Sciences Division - Medical Oncology
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Institution:
University of Oxford
Department:
Medical Sciences Division - Medical Oncology
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Medical Oncology
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Wellcome Trust Centre for Human Genetics
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Medical Oncology
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Publisher:
Macmillan Publishers Publisher's website
Journal:
European Journal of Human Genetics Journal website
Volume:
20
Pages:
203-210
Publication date:
2012
DOI:
EISSN:
1476-5438
ISSN:
1018-4813
URN:
uuid:f5ce15a3-2ba0-48b8-8d35-38ec073975f6
Local pid:
ora:6129

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