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Journal article

The potential and challenges of nanopore sequencing.

Abstract:

A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore. The nanopore provides a highly confined space within which single nucleic acid polymers can be analyzed at high throughput by one of a variety of means, and the perfect processivity that can be enforced in a narrow pore ensures that the native order of the nucleobases in a polynucleotide is reflected in the seq...

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Publication status:
Published

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Publisher copy:
10.1038/nbt.1495

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Journal:
Nature biotechnology
Volume:
26
Issue:
10
Pages:
1146-1153
Publication date:
2008-10-05
DOI:
EISSN:
1546-1696
ISSN:
1087-0156
URN:
uuid:f5cb0f5e-23ec-4c3d-99a6-042d2ad1937c
Source identifiers:
52258
Local pid:
pubs:52258

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