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Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

Abstract:

A group of mAb recognizing the 200- and/or 220-kDa determinants (CD45R) of the leukocyte common Ag such as 2H4, WR16, MD4.3, and SN130 cross-block each other showing that they recognize a closely related epitope. The antibody UCHL1 reacts with a 180-kDa determinant of the leukocyte common Ag and exhibits a reciprocal T subset distribution pattern to the CD45R group. Peripheral blood T cells were 40% positive for UCHL1 and 58 to 65% positive for the CD45R antibodies; less than 1% of cells stai...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Journal of Immunology More from this journal
Volume:
140
Issue:
7
Pages:
2171-2178
Publication date:
1988-04-01
EISSN:
1550-6606
ISSN:
0022-1767
Language:
English
Keywords:
Pubs id:
pubs:35278
UUID:
uuid:f5c1b4ca-9c23-4353-be3b-c374d4ac0c45
Local pid:
pubs:35278
Source identifiers:
35278
Deposit date:
2012-12-19

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