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From hemangioblast to hematopoietic stem cell: an endothelial connection?

Abstract:

The developmental origin of hematopoietic stem cells has been the subject of much research. Now that the developmental link between the hematopoietic system and the vasculature has been well established, questions remain regarding the precise cellular origin of definitive hematopoietic cells and at what point they branch off from the endothelial lineage. Do they emerge directly from a hemangioblast-type cell, similar to what is proposed for primitive yolk sac hematopoiesis, or are they genera...

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Publication status:
Published

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Authors


Jaffredo, T More by this author
Nottingham, W More by this author
Liddiard, K More by this author
Bollerot, K More by this author
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Journal:
Experimental hematology
Volume:
33
Issue:
9
Pages:
1029-1040
Publication date:
2005-09-05
DOI:
EISSN:
1873-2399
ISSN:
0301-472X
URN:
uuid:f5c19fd8-36f3-4a4d-8a57-4e98adffeef4
Source identifiers:
271869
Local pid:
pubs:271869

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