Journal article icon

Journal article

Rhodium-catalyzed intermolecular chelation controlled alkene and alkyne hydroacylation: synthetic scope of beta-S-substituted aldehyde substrates.

Abstract:

The use of beta-S-substituted aldehydes in rhodium-catalyzed intermolecular hydroacylation reactions is reported. Aldehydes substituted with either sulfide or thioacetal groups undergo efficient hydroacylation with a variety of electron-poor alkenes, such as enoates, in Stetter-like processes and with both electron-poor and neutral alkynes. In general, the reactions with electron-poor alkenes demonstrate good selectivity for the linear regioisomer, and the reactions with alkynes provide enone...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1021/jo060582o
Journal:
Journal of organic chemistry More from this journal
Volume:
71
Issue:
14
Pages:
5291-5297
Publication date:
2006-07-01
DOI:
EISSN:
1520-6904
ISSN:
0022-3263
Language:
English
Keywords:
Pubs id:
pubs:52468
UUID:
uuid:f5b1710c-a10c-446d-a93f-ca94d59e899a
Local pid:
pubs:52468
Source identifiers:
52468
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP