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Journal article

Pretreatment CD4 cell slope and progression to AIDS or death in HIV-infected patients initiating antiretroviral therapy--the CASCADE collaboration: a collaboration of 23 cohort studies.

Abstract:

BACKGROUND: CD4 cell count is a strong predictor of the subsequent risk of AIDS or death in HIV-infected patients initiating combination antiretroviral therapy (cART). It is not known whether the rate of CD4 cell decline prior to therapy is related to prognosis and should, therefore, influence the decision on when to initiate cART. METHODS AND FINDINGS: We carried out survival analyses of patients from the 23 cohorts of the CASCADE (Concerted Action on SeroConversion to AIDS and Death in Euro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.1000239

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More from this funder
Name:
Gottfried and Julia-Bangerter-Rhyner Foundation
Funding agency for:
Wolbers, M
More from this funder
Name:
santésuisse
Funding agency for:
Wolbers, M
Publisher:
Public Library of Science
Journal:
PLoS medicine More from this journal
Volume:
7
Issue:
2
Article number:
e1000239
Publication date:
2010-02-01
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Language:
English
Keywords:
Pubs id:
pubs:113071
UUID:
uuid:f58e2377-bd20-4793-bec9-d7a915c6b96b
Local pid:
pubs:113071
Source identifiers:
113071
Deposit date:
2012-12-19

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