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Mapping nanomechanical properties of live cells using multi-harmonic atomic force microscopy.

Abstract:

The nanomechanical properties of living cells, such as their surface elastic response and adhesion, have important roles in cellular processes such as morphogenesis, mechano-transduction, focal adhesion, motility, metastasis and drug delivery. Techniques based on quasi-static atomic force microscopy techniques can map these properties, but they lack the spatial and temporal resolution that is needed to observe many of the relevant details. Here, we present a dynamic atomic force microscopy me...

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Publication status:
Published

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Publisher copy:
10.1038/nnano.2011.186

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Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Condensed Matter Physics
Role:
Author
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Journal:
Nature nanotechnology
Volume:
6
Issue:
12
Pages:
809-814
Publication date:
2011-12-05
DOI:
EISSN:
1748-3395
ISSN:
1748-3387
URN:
uuid:f5483922-7583-46bc-a797-ca229d5c61ae
Source identifiers:
206060
Local pid:
pubs:206060

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