Investigating the burden of acute and chronic typhoid fever and the relative contribution to ongoing transmission of salmonella typhi in three urban sites in Africa and Asia

Thesis

Enteric fever is a serious public health concern in many low- and middle-income countries. However, numerous data gaps exist concerning the epidemiology and transmission of Salmonella Typhi and Paratyphi A, the causative agents of enteric fever, in different global contexts. Facility-based passive surveillance for enteric fever underestimates true incidence of disease as not all cases of infection can be captured. In typhoid endemic sites, where febrile illness is a common clinical syndrom...

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Authors: Meiring, J

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: salmonella; Asia; vaccines; epidemiology; Africa; antimicrobial resistance; typhoid fever
• Subjects: Epidemiology; Salmonella typhi; Typhoid vaccine