Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro.

Journal article

Gamma frequency (30-100 Hz) network oscillations occur in the intact hippocampus during awake, attentive behavior. Here, we explored the underlying cellular mechanisms in an in vitro model of persistent gamma-frequency oscillations, induced by bath application of 20 microm carbachol in submerged hippocampal slices at 30 +/- 1 degrees C. Current-source density analysis of the field oscillation revealed a prominent alternating sink-source pair in the perisomatic and apical dendritic regions of ...

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Authors: Hájos, N; Pálhalmi, J; Mann, E; Németh, B; Paulsen, O

• Publication status: Published
• Journal: Journal of neuroscience : the official journal of the Society for Neuroscience
• Volume: 24
• Issue: 41
• Pages: 9127-9137
• Publication date: 2004-10-01
• DOI: 10.1523/jneurosci.2113-04.2004
• EISSN: 1529-2401
• ISSN: 0270-6474
• Language: English
• Keywords: Neural Inhibition; Patch-Clamp Techniques; Pyramidal Cells; Biological Clocks; Cholinergic Agonists; Rats, Wistar; Action Potentials; Interneurons; Nerve Net; Animals; gamma-Aminobutyric Acid; Male; Electric Stimulation; Rats; Hippocampus; Time Factors