Journal article
Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner
- Abstract:
- Vδ2+ γδT cells are unconventional T cells that can be activated by cytokines without TCR signaling. Adenovirus vaccine vectors activated Vδ2+ γδT cells in an interleukin 18-, TNF-, and type I interferon-dependent manner. This stimulatory capacity was associated with adenovirus vectors of non-species C origin, including the ChAdOx1 vaccine platform.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 660.2KB, Terms of use)
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- Publisher copy:
- 10.1002/eji.202149367
Authors
- Publisher:
- Wiley
- Journal:
- European Journal of Immunology More from this journal
- Volume:
- 52
- Issue:
- 5
- Pages:
- 835-837
- Place of publication:
- Germany
- Publication date:
- 2022-01-17
- Acceptance date:
- 2021-12-14
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- Pmid:
-
34958459
- Language:
-
English
- Keywords:
- Pubs id:
-
1230493
- Local pid:
-
pubs:1230493
- Deposit date:
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2022-02-03
Terms of use
- Copyright holder:
- Provine et al.
- Copyright date:
- 2021
- Rights statement:
- © 2022 The Authors. European Journal of Immunology published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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