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Regenerant arabidopsis lineages display a distinct genome-wide spectrum of mutations conferring variant phenotypes

Abstract:

Multicellular organisms can be regenerated from totipotent differentiated somatic cell or nuclear founders [1-3]. Organisms regenerated from clonally related isogenic founders might a priori have been expected to be phenotypically invariant. However, clonal regenerant animals display variant phenotypes caused by defective epigenetic reprogramming of gene expression [2], and clonal regenerant plants exhibit poorly understood heritable phenotypic ("somaclonal") variation [4-7]. Here we show tha...

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Publisher copy:
10.1016/j.cub.2011.07.002

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Institution:
University of Oxford
Department:
Oxford
Role:
Author
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Journal:
Current Biology
Volume:
21
Issue:
16
Pages:
1385-1390
Publication date:
2011-08-23
DOI:
ISSN:
0960-9822
URN:
uuid:f4f01505-f851-4b2d-a343-cb967191dba1
Source identifiers:
179531
Local pid:
pubs:179531
Language:
English

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