Neural correlates of executive function and working memory in the 'at-risk mental state'.

Journal article

BACKGROUND: People with prodromal symptoms have a very high risk of developing psychosis. AIMS: To use functional magnetic resonance imaging to examine the neurocognitive basis of this vulnerability. METHOD: Cross-sectional comparison of regional activation in individuals with an'at-risk mental state' (at-risk group: n=17), patients with first-episode schizophreniform psychosis (psychosis group: n=10) and healthy volunteers (controls: n=15) during an overt verbal fluency task and an N-back wo...

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Authors: Broome, MR; Matthiasson, P; Fusar-Poli, P; Woolley, J; Johns, L

• Journal: British journal of psychiatry : the journal of mental science
• Volume: 194
• Issue: 1
• Pages: 25-33
• Publication date: 2009-01-01
• DOI: 10.1192/bjp.bp.107.046789
• EISSN: 1472-1465
• ISSN: 0007-1250
• Language: English
• Keywords: Female; Neuropsychological Tests; Gyrus Cinguli; Treatment Outcome; Humans; Cross-Sectional Studies; Schizophrenia; Psychotic Disorders; Young Adult; Case-Control Studies; Verbal Behavior; Memory Disorders; Adult; Magnetic Resonance Imaging; Male; Risk Factors