Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes: a prospective observational study (UKPDS 75).

Journal article

AIMS/HYPOTHESIS: The relative importance of glucose and blood pressure control in type 2 diabetes remains uncertain. We assessed interactive effects of glycaemia and systolic blood pressure (SBP) exposure on the risk of diabetic complications over time. SUBJECTS, MATERIALS AND METHODS: HbA(1c) and SBP, measured annually for a median of 10.4 years in 4,320 newly diagnosed type 2 diabetic patients from the UK Prospective Diabetes Study (UKPDS), were categorised as updated mean values <6.0, 6...

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Authors: Stratton, I; Cull, C; Adler, A; Matthews, DR; Neil, H

• Publication status: Published
• Journal: Diabetologia
• Volume: 49
• Issue: 8
• Pages: 1761-1769
• Publication date: 2006-08-01
• DOI: 10.1007/s00125-006-0297-1
• EISSN: 1432-0428
• ISSN: 0012-186X
• Language: English
• Keywords: Female; Adult; Systole; Male; Hemoglobin A, Glycosylated; Great Britain; Hypoglycemic Agents; Diabetes Complications; Proportional Hazards Models; Hypertension; Risk Factors; Health Surveys; Middle Aged; Humans; Survival Analysis; Diabetes Mellitus, Type 2; Blood Glucose