Cholesterol-dependent cytolysins.

Journal article

Abstract:: The cholesterol-dependent cytolysins (CDCs) are part of a large family of pore-forming proteins that include the human proteins perforin and the complement membrane attack complex. The activity of all family members is focused on membranes, but the proteins are themselves involved in a diverse range of phenomena. An overview of some of these phenomena is provided here, along with an historical perspective of CDCs themselves and how our understanding of their mechanism of action has developed ...
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Journal:: Advances in experimental medicine and biology More from this journal
Volume:: 677
Pages:: 56-66
Publication date:: 2010-01-01
DOI:: 10.1007/978-1-4419-6327-7_5
ISSN:: 0065-2598

Language:: English
Keywords:: Bacteria

Cholesterol

Animals

Humans

Perforin

Complement Membrane Attack Complex

Pore Forming Cytotoxic Proteins

Bacterial Toxins
Pubs id:: pubs:66101
UUID:: uuid:f4ca3303-9a61-4497-bb2d-a2fe3293ccf3
Local pid:: pubs:66101
Source identifiers:: 66101
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_f4ca33039a614497bb2da2fe3293ccf3

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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