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Journal article

Response of serum macrophage migration inhibitory factor levels to stimulation or suppression of the hypothalamo-pituitary-adrenal axis in normal subjects and patients with Cushing's disease.

Abstract:

Macrophage migration inhibitory factor (MIF) is a proinflammatory pituitary and immune cell cytokine and a critical mediator of septic shock. It has been reported that MIF is secreted in parallel with ACTH from the pituitary in response to stress or inflammatory stimuli. MIF release from immune cells is also induced rather than inhibited by glucocorticoids. It has therefore been suggested that MIF may be a novel counterregulatory hormone of glucocorticoid action that acts both as a paracrine ...

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Publication status:
Published

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Publisher copy:
10.1210/jc.87.4.1834

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Journal:
Journal of clinical endocrinology and metabolism More from this journal
Volume:
87
Issue:
4
Pages:
1834-1840
Publication date:
2002-04-01
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Language:
English
Keywords:
Pubs id:
pubs:138211
UUID:
uuid:f495eb40-ec86-4293-8af9-52286f9753fd
Local pid:
pubs:138211
Source identifiers:
138211
Deposit date:
2012-12-19

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