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Journal article

Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondria.

Abstract:

Multiple copies of the mitochondrial genome in eukaryotic cells are organized into protein-DNA complexes called nucleoids. Mitochondrial genome repair mechanisms have been reported, but they are less well characterized than their nuclear counterparts. To expand our knowledge of mitochondrial genome maintenance, we have studied the localization of the BRCA1 protein, known to be involved in nuclear repair pathways. Our confocal and immunoelectron microscopy results show that BRCA1 is present in...

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Publication status:
Published

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Publisher copy:
10.1091/mbc.e04-10-0895

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Journal:
Molecular biology of the cell
Volume:
16
Issue:
2
Pages:
997-1010
Publication date:
2005-02-05
DOI:
EISSN:
1939-4586
ISSN:
1059-1524
URN:
uuid:f47cf60d-56f0-4473-90c5-09d30723bcb5
Source identifiers:
18044
Local pid:
pubs:18044

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