- Abstract:
-
Multiple copies of the mitochondrial genome in eukaryotic cells are organized into protein-DNA complexes called nucleoids. Mitochondrial genome repair mechanisms have been reported, but they are less well characterized than their nuclear counterparts. To expand our knowledge of mitochondrial genome maintenance, we have studied the localization of the BRCA1 protein, known to be involved in nuclear repair pathways. Our confocal and immunoelectron microscopy results show that BRCA1 is present in...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1091/mbc.e04-10-0895
-
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- Journal:
- Molecular biology of the cell
- Volume:
- 16
- Issue:
- 2
- Pages:
- 997-1010
- Publication date:
- 2005-02-05
- DOI:
- EISSN:
-
1939-4586
- ISSN:
-
1059-1524
- URN:
-
uuid:f47cf60d-56f0-4473-90c5-09d30723bcb5
- Source identifiers:
-
18044
- Local pid:
- pubs:18044
- Language:
- English
- Keywords:
- Copyright date:
- 2005
Journal article
Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondria.
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