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Properties of murine (CD8+)CD27- T cells.

Abstract:

In humans, loss of CD27 expression is associated with the stable acquisition of effector functions by CD8+ T cells. We found that murine (CD8+)CD27- T cells were confined to the primed CD62L(dull/-)CD44(bright)CCR7- T cell population. (CD8+)CD27- T cells were absent from lymph nodes but could be found in blood, spleen and in non-lymphoid organs such as lung and liver. Late after primary influenza virus infection, low percentages of antigen-specific CD27- cells emerged in the lung and spleen. ...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200425770

Authors


Tesselaar, K More by this author
Hooibrink, B More by this author
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Journal:
European journal of immunology
Volume:
35
Issue:
11
Pages:
3131-3141
Publication date:
2005-11-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:f46941ca-842a-4908-9a15-9eadf3cfb14a
Source identifiers:
4628
Local pid:
pubs:4628

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