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Journal article

Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis.

Abstract:

Quantitative and qualitative protein characteristics are regulated at genomic, transcriptomic, and posttranscriptional levels. Here, we integrated in-depth transcriptome and proteome analyses of liver tissues from two rat strains to unravel the interactions within and between these layers. We obtained peptide evidence for 26,463 rat liver proteins. We validated 1,195 gene predictions, 83 splice events, 126 proteins with nonsynonymous variants, and 20 isoforms with nonsynonymous RNA editing. Q...

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Publication status:
Published

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Journal:
Cell reports
Volume:
5
Issue:
5
Pages:
1469-1478
Publication date:
2013-12-05
DOI:
EISSN:
2211-1247
ISSN:
2211-1247
URN:
uuid:f42042f3-9840-476c-8052-b008e6952102
Source identifiers:
441557
Local pid:
pubs:441557

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