Journal article icon

Journal article

Failure of a new protocol to improve treatment results in paediatric lymphoblastic leukaemia: lessons from the UK Medical Research Council trials UKALL X and UKALL XI.

Abstract:

The impact of various types of intensification therapy was examined in a cohort of 3617 children aged 1-14 years with acute lymphoblastic leukaemia (ALL) enrolled in the Medical Research Council (MRC) UKALL X (1985-90) and UKALL XI (1990-97) trials. UKALL XI was modified in 1992 to incorporate the "best arm" of UKALL X with two 5-d intensification blocks at 5 and 20 weeks, and an additional randomization in respect of a third intensification at 35 weeks but omission of two consecutive injecti...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
British journal of haematology
Volume:
118
Issue:
2
Pages:
445-455
Publication date:
2002-08-05
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
URN:
uuid:f413aa9d-b917-4ccb-96db-ea1e6a80eb93
Source identifiers:
88467
Local pid:
pubs:88467

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP