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Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31.

Abstract:

BACKGROUND AND AIMS: Recent molecular data suggest that genetic factors may underlie the disease heterogeneity observed in both ulcerative colitis (UC) and Crohn's disease (CD). A locus on chromosome 5q has been implicated in susceptibility to CD, and recently refined by linkage disequilibrium mapping to a conserved 250 kb haplotype (5q31). No data regarding the contribution of this locus to clinical phenotype exist. In this case control study, we investigated the contribution of this haplot...

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Publication status:
Published

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Publisher copy:
10.1136/gut.52.8.1133

Authors


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Journal:
Gut
Volume:
52
Issue:
8
Pages:
1133-1139
Publication date:
2003-08-01
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
Source identifiers:
54016
Language:
English
Keywords:
Pubs id:
pubs:54016
UUID:
uuid:f40771a7-21ea-4f9f-b95d-adcc58739a4b
Local pid:
pubs:54016
Deposit date:
2012-12-19

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