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A malaria scavenger receptor-like protein essential for parasite development.

Abstract:

Malaria parasites suffer severe losses in the mosquito as they cross the midgut, haemolymph and salivary gland tissues, in part caused by immune responses of the insect. The parasite compensates for these losses by multiplying during the oocyst stage to form the infectious sporozoites. Upon human infection, malaria parasites are again attenuated by sustained immune attack. Here, we report a single copy gene that is highly conserved amongst Plasmodium species that encodes a secreted protein na...

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Journal:
Molecular microbiology
Volume:
45
Issue:
6
Pages:
1473-1484
Publication date:
2002-09-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:f3f6ad14-48ab-4517-850f-95dff9d41bac
Source identifiers:
268463
Local pid:
pubs:268463

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