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Multichannel mapping of fetal magnetocardiogram in an unshielded hospital setting.

Abstract:
OBJECTIVES: To evaluate the feasibility of unshielded in-hospital multichannel mapping of fetal magnetocardiogram (FMCG), with a 36-channel system for standard adult magnetocardiographic (MCG) recordings, and its reliability according to the recommended standards for FMCG. METHODS: FMCG was ambulatory mapped with a 36-channel MCG system, in six normal pregnancies at different gestational ages. MCG analysis included adaptive digital filtering of 50 Hz, signal averaging, reconstruction of magnetic field distribution (MFD) and source localization. Fixed Point Independent Component Analysis algorithm (FastICA) was used to reconstruct the FMCG, separating them from maternal contamination and noise. RESULTS: The quality of FMCG recorded after the 32nd gestational week and reconstructed with FastICA was close to FMCG obtained in shielded rooms, and good enough to measure cardiac intervals and heart rate variability parameters. In two cases, reconstruction of the MFD during the QRS allowed three-dimensional localization of ventricular sources. CONCLUSIONS: A first demonstration has been given that multichannel mapping of FMCG can be performed in unshielded clinical environments, with resolution good enough for contactless assessment of fetal cardiac electrophysiology. FastICA processing on unshielded FMCG, recorded after the 32nd week, provided beat-to-beat analysis and heart rate variability assessment. Further work is needed to improve signal reconstruction in early pregnancy.

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Publisher copy:
10.1002/pd.1160

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author


Journal:
Prenatal diagnosis More from this journal
Volume:
25
Issue:
5
Pages:
376-382
Publication date:
2005-05-01
DOI:
EISSN:
1097-0223
ISSN:
0197-3851


Language:
English
Keywords:
Pubs id:
pubs:364131
UUID:
uuid:f3e9726f-1d60-421c-8736-87ef62368da7
Local pid:
pubs:364131
Source identifiers:
364131
Deposit date:
2013-11-16
ARK identifier:

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