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Lymphocyte subpopulations in the human small intestine. The findings in normal mucosa and in the mucosa of patients with adult coeliac disease.

Abstract:

Lymphocyte subpopulations in human small intestinal mucosa have been studied using an immunofluorescence technique on tissue sections. In the normal intestine, the majority of intraepithelial lymphocytes (IEL) were of suppressor-cytotoxic phenotype (HuTLA+ UCHTI+ OKT8+ OKT4-; 84%). Only one-third of these OKT8+IEL reacted with anti-Leu-1, and antibody directed towards a 67,000 dalton antigen found on peripheral blood T cells. IEL failed to express the activation antigen, Tac, and also lacked ...

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Publication status:
Published

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Authors


Janossy, G More by this author
Jewell, DP More by this author
Journal:
Clinical and experimental immunology
Volume:
52
Issue:
1
Pages:
219-228
Publication date:
1983-04-05
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:f3c556cf-48d7-4c7a-ae1d-c54a1cbc35e5
Source identifiers:
135758
Local pid:
pubs:135758

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