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Diagnostic utility of aP2/FABP4 expression in soft tissue tumours

Abstract:

Adipocyte P2 (aP2), also known as fatty acid-binding protein 4 (FABP4), is a fatty acid-binding protein found in the cytoplasm of cells of adipocyte differentiation. In this study, we examined a large number of soft tissue tumours with a commercial polyclonal anti-aP2/FABP4 antibody and a newly developed mouse monoclonal antibody raised against this protein to determine the diagnostic utility of aP2/FABP4 as a marker of tumours of adipose differentiation. A mouse monoclonal antibody, clone 17...

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Publication status:
Published

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Publisher copy:
10.1007/s00428-013-1392-6

Authors


Kashima, TG More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences
Athanasou, NA More by this author
Journal:
VIRCHOWS ARCHIV
Volume:
462
Issue:
4
Pages:
465-472
Publication date:
2013-04-05
DOI:
EISSN:
1432-2307
ISSN:
0945-6317
URN:
uuid:f3c1744a-ef56-450e-a562-0816a7d8b829
Source identifiers:
403354
Local pid:
pubs:403354
Language:
English
Keywords:

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